Direct therapeutic intervention for advanced pancreatic cancer
نویسندگان
چکیده
منابع مشابه
A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.
There is an enormous gap between the antiproliferative and in vivo antitumor efficacy of gemcitabine in cell line-based models and its clinical efficacy. This may be due to insensitiveness of the precursor, cancer stem cell (CSC) compartment to cytotoxic agents. The hedgehog pathway is associated with CSC signaling and control. We used a direct xenograft model of pancreatic cancer and a two-sta...
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ژورنال
عنوان ژورنال: World Journal of Clinical Oncology
سال: 2015
ISSN: 2218-4333
DOI: 10.5306/wjco.v6.i6.216